[Gentoo Prefix][1] now supports Itanium Linux and AIX-6.1 (with caveats). ia64-linux mostly works out of the box. There is one small issue with scanelf which I would like to fix if I ever find the time. (‘scanelf(9292): unaligned access to …’ – low priority because everything still appears to work). We previously supported ia64-linux but it was removed because we didn’t think anyone used it – and no one responded when we asked.